Metabolic Responses in Endothelial Cells Following Exposure to Ketone Bodies
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چکیده
منابع مشابه
Metabolic Responses in Endothelial Cells Following Exposure to Ketone Bodies
The ketogenic diet (KD) is a high-fat, low-carbohydrate diet based on the induction of the synthesis of ketone bodies (KB). Despite its widespread use, the systemic impact of KD is not completely understood. The purpose of this study was to evaluate the effects of physiological levels of KB on HMEC-1 endothelial cells. To this aim, DNA oxidative damage and the activation of Nrf2, a known transc...
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Ketosis, meaning elevation of D-beta-hydroxybutyrate (R-3hydroxybutyrate) and acetoacetate, has been central to starving man's survival by providing nonglucose substrate to his evolutionarily hypertrophied brain, sparing muscle from destruction for glucose synthesis. Surprisingly, D-beta-hydroxybutyrate (abbreviated "betaOHB") may also provide a more efficient source of energy for brain per uni...
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ژورنال
عنوان ژورنال: Nutrients
سال: 2018
ISSN: 2072-6643
DOI: 10.3390/nu10020250